excision repair การใช้

• It induces DNA lesions usually corrected by nucleotide excision repair.
• Nucleotide excision repair is a more general mechanism for repair of lesions.
• CSB is involved in the base excision repair ( BER ) pathway.
• NTHL1 is usually involved in removing oxidative pyrimidine lesions through base excision repair.
• NTHL1 catalyses the first step in base excision repair.
• It is involved in transcription-coupled excision repair.
• This process is known as nucleotide excision repair.
• This block can only be relieved by the DNA repair system nucleotide excision repair.
• WRN is a member of the nonhomologous end joining, and base excision repair.
• This gene encodes a component of the nucleotide excision repair ( NER ) pathway.
• This allows DNA repair mediated by endogenous mechanisms like the nucleotide excision repair system.
• A schematic representation of models for the nucleotide excision repair pathway controlled by Uvr proteins.
• Some examples of epimutations in base excision repair genes that occur in cancers are summarized below.
• Nucleotide excision repair is more complex in eukaryotes than prokaryotes, but the general principle is similar.
• Next to a vital function in transcription initiation, TFIIH is also involved in nucleotide excision repair.
• It initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired.
• AP sites can be formed by spontaneous depurination, but also occur as intermediates in base excision repair.
• AICDA can deaminate 5-methylcytosine, which can then be replaced with cytosine by base excision repair.
• Several recent publications have investigated the state and impact of nucleotide excision repair in colorectal and breast carcinomas.
• PARPs are enzymes that are activated by DNA strand breaks and play a role in DNA base excision repair.